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产品简介
| 靶标 | M6A |
| 别名 | 6-N-Methyladenoside;m6A;N6-methyladenosine;M6A |
| 宿主 | Mouse |
| 稀释比例 | RIP 1:1000-4000;ELISA 1:2000-20000;DOT BLOT 1:1000-4000. |
| 保存 | Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles. |
| 储存液 | PBS with 0.02% sodium azide and 50% glycerol pH 7.3. |
| 亚型 | IgG3 |
| 纯化方法 | Affinity purification |
| 背景资料 | m6A (N6-methyladenosine) is the most abundant internal modification in mammalian mRNA. This modification is installed by the m6A methyltransferases or termed writerssuch as METTL3 and METTL14, and can be reversed by demethylases that serve as erasers such as FTO and ALKBH5. The stability of m6A-modified mRNA is regulated by m6A reader protein YTHDFs, which recognizes m6A and reduces the stability of target transcripts. m6A modification and its regulatory proteins play critical roles in cancer pathogenesis and progression. m6A modification is also invovled in viruses life cycles, suggesting that drugs targets to m6A pathway could be used for antiviral thereapy. |
| 克隆类型 | Monoclonal antibody |
| 规格 | 50ul100ul |
注意：
1.本产品仅供科研使用。请勿用于医药、临床诊断或治疗，食品及化妆品等用途。请勿存放于普通住宅区。
2.为了您的安全和健康，请穿好实验服并佩戴一次性手套和口罩操作。
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