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产品简介
| 靶标 | CYP7A1 |
| 别名 | CYP7A1;CP7A;CYP7;CYPVII |
| 宿主 | Rabbit |
| 稀释比例 | WB 1:500-2000. IF 1:50-200 |
| Gene ID | 1581 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| Swiss Prot | P22680 |
| 蛋白分子量 | 57kDa |
| 储存液 | Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. |
| 亚细胞定位 | Endoplasmic reticulum membrane,Microsome membrane,Peripheral membrane protein |
| 免疫原 | Recombinant protein of human CYP7A1 |
| 亚型 | IgG |
| 纯化方法 | Affinity purification |
| 背景资料 | This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This endoplasmic reticulum membrane protein catalyzes the first reaction in the cholesterol catabolic pathway in the liver, which converts cholesterol to bile acids. This reaction is the rate limiting step and the major site of regulation of bile acid synthesis, which is the primary mechanism for the removal of cholesterol from the body. Polymorphisms in the promoter of this gene are associated with defects in bile acid synthesis. |
| Public Immunogen Range | 20-280aa |
| 克隆类型 | Polyclonal Antibody |
| 交叉反应 | HumanMouseRat |
| 应用 | WBIF |
| 规格 | 50ul100ul |
注意：
1.本产品仅供科研使用。请勿用于医药、临床诊断或治疗，食品及化妆品等用途。请勿存放于普通住宅区。
2.为了您的安全和健康，请穿好实验服并佩戴一次性手套和口罩操作。
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