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产品简介
| 英文名称 | Anti-LIG4 Polyclonal Antibody |
| 靶标 | LIG4 |
| 别名 | DNA ligase 4;DNA ligase IV;Polydeoxyribonucleotide synthase [ATP] 4; |
| 宿主 | Rabbit |
| 预测交叉反应 | Chimpanzee;Chicken;Hamster |
| 稀释比例 | IHC 1:50-200. |
| Gene ID | 3981 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| Swiss Prot | P49917 |
| 蛋白分子量 | 104kDa |
| 储存液 | Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. |
| 亚细胞定位 | Nucleus Cytoplasm |
| 免疫原 | A synthetic peptide of human LIG4 |
| 亚型 | IgG |
| 纯化方法 | Affinity purification |
| 背景资料 | Efficiently joins single-strand breaks in a double-stranded polydeoxynucleotide in an ATP-dependent reaction. Involved in DNA non-homologous end joining (NHEJ) required for double-strand break repair and V(D)J recombination. The LIG4-XRCC4 complex is responsible for the NHEJ ligation step, and XRCC4 enhances the joining activity of LIG4. Binding of the LIG4-XRCC4 complex to DNA ends is dependent on the assembly of the DNA-dependent protein kinase complex DNA-PK to these DNA ends. |
| Public Immunogen Range | 425-475/911aa |
| 克隆类型 | Polyclonal Antibody |
| 交叉反应 | Human;Mouse |
| 应用 | IHC |
| 规格 | 50ul100ul |
注意：
1.本产品仅供科研使用。请勿用于医药、临床诊断或治疗，食品及化妆品等用途。请勿存放于普通住宅区。
2.为了您的安全和健康，请穿好实验服并佩戴一次性手套和口罩操作。
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