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产品简介
英文名称 | Anti-XRN2 Polyclonal Antibody |
靶标 | XRN2 |
别名 | 5' 3' exoribonuclease 2;DHM1 like protein;DHP protein;XRN 2 |
宿主 | Rabbit |
预测交叉反应 | Chimpanzee;Chicken |
稀释比例 | IHC 1:100-300. |
Gene ID | 22803 |
保存 | Store at -20°C. Avoid freeze / thaw cycles. |
Swiss Prot | Q9H0D6 |
蛋白分子量 | 100/108kDa |
储存液 | Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. |
亚细胞定位 | Nucleus |
免疫原 | A synthetic peptide of human XRN2 |
亚型 | IgG |
纯化方法 | Affinity purification |
背景资料 | Possesses 5'->3' exoribonuclease activity (By similarity). May promote the termination of transcription by RNA polymerase II. During transcription termination, cleavage at the polyadenylation site liberates a 5' fragment which is subsequently processed to form the mature mRNA and a 3' fragment which remains attached to the elongating polymerase. The processive degradation of this 3' fragment by this protein may promote termination of transcription. Binds to RNA polymerase II (RNAp II) transcription termination R-loops formed by G-rich pause sites. |
Public Immunogen Range | 500-550/950aa |
克隆类型 | Polyclonal Antibody |
交叉反应 | Human;Mouse |
应用 | IHC |
规格 | 50ul100ul |
注意:
1.本产品仅供科研使用。请勿用于医药、临床诊断或治疗,食品及化妆品等用途。请勿存放于普通住宅区。
2.为了您的安全和健康,请穿好实验服并佩戴一次性手套和口罩操作。
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