暂无数据
产品名称
起订量
单价(含增值税)
库存(PCS)
起订数量
产品简介
英文名称 | Anti-EPHB1/2/3/4 Polyclonal Antibody |
靶标 | EPHB1/2/3/4 |
别名 | CAPB;DRT;EK5;EPHT3;ERK;Hek5;PCBC;Tyro5 |
宿主 | Rabbit |
稀释比例 | WB 1:1000-3000. |
Gene ID | 2047/2048/2049/2050 |
保存 | Store at -20°C. Avoid freeze / thaw cycles. |
Swiss Prot | P54762/P29323/P54753/P54760 |
蛋白分子量 | 110/117kDa |
储存液 | Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. |
亚细胞定位 | Cell membrane Cytoplasm |
免疫原 | A synthetic peptide of human EPHB1/2/3/4 |
亚型 | IgG |
纯化方法 | Octanoic acid-ammonium sulfate precipitation |
背景资料 | Receptor tyrosine kinase which binds promiscuously transmembrane ephrin-B family ligands residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. The signaling pathway downstream of the receptor is referred to as forward signaling while the signaling pathway downstream of the ephrin ligand is referred to as reverse signaling. Functions in axon guidance during development. Involved in the guidance of commissural axons, that form a major interhemispheric connection between the 2 temporal lobes of the cerebral cortex. Also involved in guidance of contralateral inner ear efferent growth cones at the midline and of retinal ganglion cell axons to the optic disk. In addition to axon guidance, also regulates dendritic spines development and maturation and stimulates the formation of excitatory synapses. Upon activation by EFNB1, abolishes the ARHGEF15-mediated negative regulation on excitatory synapse formation. Controls other aspects of development including angiogenesis, palate development and in inner ear development through regulation of endolymph production. Forward and reverse signaling through the EFNB2/EPHB2 complex regulate movement and adhesion of cells that tubularize the urethra and septate the cloaca. May function as a tumor suppressor. May be involved in the regulation of platelet activation and blood coagulation. |
Public Immunogen Range | 585-635/987aa |
克隆类型 | Polyclonal Antibody |
交叉反应 | Human |
应用 | WB |
规格 | 50ul100ul |
注意:
1.本产品仅供科研使用。请勿用于医药、临床诊断或治疗,食品及化妆品等用途。请勿存放于普通住宅区。
2.为了您的安全和健康,请穿好实验服并佩戴一次性手套和口罩操作。
暂无数据
我要询价
*联系方式:
(可以是QQ、MSN、电子邮箱、电话等,您的联系方式不会被公开)
*内容: