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产品简介
| 英文名称 | Anti-CSE1L Polyclonal Antibody |
| 靶标 | CSE1L |
| 别名 | CAS;CSE1;XPO2 |
| 宿主 | Rabbit |
| 预测交叉反应 | Cow;Chimpanzee;Fish;Zebrafish;Xenopus laevis |
| 稀释比例 | IHC 1:50-200. |
| Gene ID | 1434 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| Swiss Prot | P55060 |
| 蛋白分子量 | 26/104/107/110kDa |
| 储存液 | Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. |
| 亚细胞定位 | Cytoplasm Nucleus |
| 免疫原 | A synthetic peptide of human CSE1L |
| 亚型 | IgG |
| 纯化方法 | Affinity purification |
| 背景资料 | Export receptor for importin-alpha. Mediates importin-alpha re-export from the nucleus to the cytoplasm after import substrates (cargos) have been released into the nucleoplasm. In the nucleus binds cooperatively to importin-alpha and to the GTPase Ran in its active GTP-bound form. Docking of this trimeric complex to the nuclear pore complex (NPC) is mediated through binding to nucleoporins. Upon transit of a nuclear export complex into the cytoplasm, disassembling of the complex and hydrolysis of Ran-GTP to Ran-GDP (induced by RANBP1 and RANGAP1, respectively) cause release of the importin-alpha from the export receptor. CSE1L/XPO2 then return to the nuclear compartment and mediate another round of transport. The directionality of nuclear export is thought to be conferred by an asymmetric distribution of the GTP- and GDP-bound forms of Ran between the cytoplasm and nucleus. |
| Public Immunogen Range | 265-315/971aa |
| 克隆类型 | Polyclonal Antibody |
| 交叉反应 | Human;Mouse |
| 应用 | IHC |
| 规格 | 50ul100ul |
注意：
1.本产品仅供科研使用。请勿用于医药、临床诊断或治疗，食品及化妆品等用途。请勿存放于普通住宅区。
2.为了您的安全和健康，请穿好实验服并佩戴一次性手套和口罩操作。
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