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产品简介
英文名称 | Anti-CD101 Polyclonal Antibody |
靶标 | CD101 |
别名 | EWI101;IGSF2;V7 |
宿主 | Rabbit |
稀释比例 | IHC 1:50-200. |
Gene ID | 9398 |
保存 | Store at -20°C. Avoid freeze / thaw cycles. |
Swiss Prot | Q93033 |
蛋白分子量 | 115kDa |
储存液 | Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. |
亚细胞定位 | Cell membrane Secreted |
免疫原 | A synthetic peptide of human CD101 |
亚型 | IgG |
纯化方法 | Affinity purification |
背景资料 | Plays a role as inhibitor of T-cells proliferation induced by CD3. Inhibits expression of IL2RA on activated T-cells and secretion of IL2. Inhibits tyrosine kinases that are required for IL2 production and cellular proliferation. Inhibits phospholipase C-gamma-1/PLCG1 phosphorylation and subsequent CD3-induced changes in intracellular free calcium. Prevents nuclear translocation of nuclear factor of activated T-cell to the nucleus. Plays a role in the inhibition of T-cell proliferation via IL10 secretion by cutaneous dendritic cells. May be a marker of CD4+ CD56+ leukemic tumor cells. |
Public Immunogen Range | 325-375/1021aa |
克隆类型 | Polyclonal Antibody |
交叉反应 | Human |
应用 | IHC |
规格 | 50ul100ul |
注意:
1.本产品仅供科研使用。请勿用于医药、临床诊断或治疗,食品及化妆品等用途。请勿存放于普通住宅区。
2.为了您的安全和健康,请穿好实验服并佩戴一次性手套和口罩操作。
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