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产品简介
英文名称 | Anti-RAPGEF1 Polyclonal Antibody |
靶标 | RAPGEF1 |
别名 | C3G;GRF2 |
宿主 | Rabbit |
稀释比例 | IHC 1:100-300. |
Gene ID | 2889 |
保存 | Store at -20°C. Avoid freeze / thaw cycles. |
Swiss Prot | Q13905 |
蛋白分子量 | 116/120/122kDa |
储存液 | Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. |
亚细胞定位 | Cytoplasm |
免疫原 | A synthetic peptide of human RAPGEF1 |
亚型 | IgG |
纯化方法 | Affinity purification |
背景资料 | Guanine nucleotide-releasing protein that binds to SH3 domain of CRK and GRB2/ASH. Transduces signals from CRK to activate RAS. Involved in cell branching and adhesion mediated by BCAR1-CRK-RAPGEF1 signaling and activation of RAP1. Plays a role in the establishment of basal endothelial barrier function. Plays a role in nerve growth factor (NGF)-induced sustained activation of Rap1 and neurite outgrowth. |
Public Immunogen Range | 465-515/1077aa |
克隆类型 | Polyclonal Antibody |
交叉反应 | Human |
应用 | IHC |
规格 | 50ul100ul |
注意:
1.本产品仅供科研使用。请勿用于医药、临床诊断或治疗,食品及化妆品等用途。请勿存放于普通住宅区。
2.为了您的安全和健康,请穿好实验服并佩戴一次性手套和口罩操作。
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