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产品简介
英文名称 | Anti-MAP3K9 Polyclonal Antibody |
靶标 | MAP3K9 |
别名 | MLK1;PRKE1 |
宿主 | Rabbit |
稀释比例 | WB 1:1000-3000. |
Gene ID | 4293 |
保存 | Store at -20°C. Avoid freeze / thaw cycles. |
Swiss Prot | P80192 |
蛋白分子量 | 122/123kDa |
储存液 | Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. |
亚细胞定位 | Cytoplasm |
免疫原 | A synthetic peptide of human MAP3K9 |
亚型 | IgG |
纯化方法 | Affinity purification |
背景资料 | Serine/threonine kinase which acts as an essential component of the MAP kinase signal transduction pathway. Plays an important role in the cascades of cellular responses evoked by changes in the environment. Once activated, acts as an upstream activator of the MKK/JNK signal transduction cascade through the phosphorylation of MAP2K4/MKK4 and MAP2K7/MKK7 which in turn activate the JNKs. The MKK/JNK signaling pathway regulates stress response via activator protein-1 (JUN) and GATA4 transcription factors. Plays also a role in mitochondrial death signaling pathway, including the release cytochrome c, leading to apoptosis. |
Public Immunogen Range | 520-570/1104aa |
克隆类型 | Polyclonal Antibody |
交叉反应 | Human;Mouse |
应用 | WB |
规格 | 50ul100ul |
注意:
1.本产品仅供科研使用。请勿用于医药、临床诊断或治疗,食品及化妆品等用途。请勿存放于普通住宅区。
2.为了您的安全和健康,请穿好实验服并佩戴一次性手套和口罩操作。
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