暂无数据
产品名称
起订量
单价(含增值税)
库存(PCS)
起订数量
产品简介
| 英文名称 | Anti-UGT1A9 Polyclonal Antibody |
| 靶标 | UGT1A9 |
| 别名 | UGT1A9;UDPGT 1-9;UGT1*9;UGT1-09;UGT1.9;UGT-1I;UGT1I;lugP4;GNT1;UGT1 |
| 宿主 | Rabbit |
| 稀释比例 | WB 1:1000-3000;IHC 1:100-300. |
| Gene ID | 54600 |
| 保存 | Store at -42°C. Avoid freeze / thaw cycles. |
| Swiss Prot | O60656 |
| 蛋白分子量 | 50/60kDa |
| 储存液 | Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.25. |
| 亚细胞定位 | Cytoplasm |
| 免疫原 | Recombinant protein of human UGT1A9 |
| 亚型 | IgG |
| 纯化方法 | Affinity purification |
| 背景资料 | UDP-glucuronosyltransferase (UGT) that catalyzes phase II biotransformation reactions in which lipophilic substrates are conjugated with glucuronic acid to increase the metabolite's water solubility, thereby facilitating excretion into either the urine or bile (PubMed:12181437, PubMed:15472229, PubMed:15470161, PubMed:18004212, PubMed:18052087, PubMed:18674515, PubMed:19545173). Essential for the elimination and detoxification of drugs, xenobiotics and endogenous compounds (PubMed:12181437, PubMed:18004212). Catalyzes the glucuronidation of endogenous estrogen hormones such as estradiol and estrone (PubMed:15472229). Also catalyzes the glucuronidation of the isoflavones genistein, daidzein, glycitein, formononetin, biochanin A and prunetin, which are phytoestrogens with anticancer and cardiovascular properties (PubMed:18052087, PubMed:19545173). Involved in the glucuronidation of the AGTR1 angiotensin receptor antagonist caderastan, a drug which can inhibit the effect of angiotensin II (PubMed:18674515). Involved in the biotransformation of 7-ethyl-10-hydroxycamptothecin (SN-38), the pharmacologically active metabolite of the anticancer drug irinotecan (PubMed:12181437, PubMed:20610558). Also metabolizes mycophenolate, an immunosuppressive agent (PubMed:15470161, PubMed:18004212).Lacks UGT glucuronidation activity but acts as a negative regulator of isoform 1. |
| Public Immunogen Range | 180-480aa |
| 克隆类型 | Polyclonal Antibody |
| 交叉反应 | Human;Mouse |
| 应用 | WB;IHC |
| 规格 | 50ul100ul |
注意：
1.本产品仅供科研使用。请勿用于医药、临床诊断或治疗，食品及化妆品等用途。请勿存放于普通住宅区。
2.为了您的安全和健康，请穿好实验服并佩戴一次性手套和口罩操作。
暂无数据
我要询价
*联系方式：
(可以是QQ、MSN、电子邮箱、电话等，您的联系方式不会被公开)
*内容：
