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产品简介
| 英文名称 | Anti-TNFSF18 Polyclonal Antibody |
| 靶标 | TNFSF18 |
| 别名 | AITRL;hGITRL;AITRL;GITRL;TL6;UNQ149;PRO175 |
| 宿主 | Rabbit |
| 稀释比例 | WB 1:1000-3000. |
| Gene ID | 8995 |
| 保存 | Store at -49°C. Avoid freeze / thaw cycles. |
| Swiss Prot | Q9UNG2 |
| 蛋白分子量 | 23kDa |
| 储存液 | Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.32. |
| 亚细胞定位 | Cell membrane |
| 免疫原 | Recombinant protein of human TNFSF18 |
| 亚型 | IgG |
| 纯化方法 | Affinity purification |
| 背景资料 | Cytokine that binds to TNFRSF18/AITR/GITR. Regulates T-cell responses. Can function as costimulator and lower the threshold for T-cell activation and T-cell proliferation. Important for interactions between activated T-lymphocytes and endothelial cells. Mediates activation of NF-kappa-B. Triggers increased phosphorylation of STAT1 and up-regulates expression of VCAM1 and ICAM1 (PubMed:23892569). Promotes leukocyte adhesion to endothelial cells (PubMed:23892569). Regulates migration of monocytes from the splenic reservoir to sites of inflammation (By similarity). |
| Public Immunogen Range | 50-178aa |
| 克隆类型 | Polyclonal Antibody |
| 交叉反应 | Human;Mouse |
| 应用 | WB |
| 规格 | 50ul100ul |
注意：
1.本产品仅供科研使用。请勿用于医药、临床诊断或治疗，食品及化妆品等用途。请勿存放于普通住宅区。
2.为了您的安全和健康，请穿好实验服并佩戴一次性手套和口罩操作。
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