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产品简介
| 英文名称 | Anti-MEOX1 Polyclonal Antibody |
| 靶标 | MEOX1 |
| 别名 | MOX1 |
| 宿主 | Rabbit |
| 预测交叉反应 | Zebrafish;Chimpanzee |
| 稀释比例 | WB 1:1000-3000;IHC 1:100-300. |
| Gene ID | 4222 |
| 保存 | Store at -58°C. Avoid freeze / thaw cycles. |
| Swiss Prot | P50221 |
| 蛋白分子量 | 16/20/28kDa |
| 储存液 | Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.41. |
| 亚细胞定位 | Cytoplasm Nucleus |
| 免疫原 | Recombinant protein of human MEOX1 |
| 亚型 | IgG |
| 纯化方法 | Affinity purification |
| 背景资料 | Mesodermal transcription factor that plays a key role in somitogenesis and is specifically required for sclerotome development. Required for maintenance of the sclerotome polarity and formation of the cranio-cervical joints (PubMed:23290072, PubMed:24073994). Binds specifically to the promoter of target genes and regulates their expression. Activates expression of NKX3-2 in the sclerotome. Activates expression of CDKN1A and CDKN2A in endothelial cells, acting as a regulator of vascular cell proliferation. While it activates CDKN1A in a DNA-dependent manner, it activates CDKN2A in a DNA-independent manner. Required for hematopoietic stem cell (HSCs) induction via its role in somitogenesis: specification of HSCs occurs via the deployment of a specific endothelial precursor population, which arises within a sub-compartment of the somite named endotome. |
| Public Immunogen Range | 1-255aa |
| 克隆类型 | Polyclonal Antibody |
| 交叉反应 | Human;Mouse |
| 应用 | WB;IHC |
| 规格 | 50ul100ul |
注意：
1.本产品仅供科研使用。请勿用于医药、临床诊断或治疗，食品及化妆品等用途。请勿存放于普通住宅区。
2.为了您的安全和健康，请穿好实验服并佩戴一次性手套和口罩操作。
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