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产品简介
英文名称 | Anti-INTU Polyclonal Antibody |
靶标 | INTU |
别名 | Protein inturned;KIAA1284;PDZD6;PDZK6 |
宿主 | Rabbit |
预测交叉反应 | Bovine;ZebraFish |
稀释比例 | WB 1:1000-3000. |
Gene ID | 27152 |
保存 | Store at -63°C. Avoid freeze / thaw cycles. |
Swiss Prot | Q9ULD6 |
蛋白分子量 | 46/49/104/106kDa |
储存液 | Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.46. |
亚细胞定位 | Cytoplasm |
免疫原 | Recombinant protein of human INTU |
亚型 | IgG |
纯化方法 | Affinity purification |
背景资料 | Plays a key role in ciliogenesis and embryonic development. Regulator of cilia formation by controlling the organization of the apical actin cytoskeleton and the positioning of the basal bodies at the apical cell surface, which in turn is essential for the normal orientation of elongating ciliary microtubules. Plays a key role in definition of cell polarity via its role in ciliogenesis but not via conversion extension. Has an indirect effect on hedgehog signaling (By similarity). Proposed to function as core component of the CPLANE (ciliogenesis and planar polarity effectors) complex involved in the recruitment of peripheral IFT-A proteins to basal bodies (PubMed:27158779). |
Public Immunogen Range | 1-350aa |
克隆类型 | Polyclonal Antibody |
交叉反应 | Human;Mouse;Rat |
应用 | WB |
规格 | 50ul100ul |
注意:
1.本产品仅供科研使用。请勿用于医药、临床诊断或治疗,食品及化妆品等用途。请勿存放于普通住宅区。
2.为了您的安全和健康,请穿好实验服并佩戴一次性手套和口罩操作。
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