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产品简介
| 英文名称 | Anti-MORF4L1 Polyclonal Antibody |
| 靶标 | MORF4L1 |
| 别名 | MORF4L1;Eaf3;FWP006;HsT17725;MEAF3;MORFRG15;MRG15;S863-6;mortality factor 4 like 1 |
| 宿主 | Rabbit |
| 预测交叉反应 | Gorilla |
| 稀释比例 | WB 1:1000-3000. |
| Gene ID | 10933 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| Swiss Prot | Q9UBU8 |
| 蛋白分子量 | 27/37/41kDa |
| 储存液 | Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. |
| 亚细胞定位 | Nucleus |
| 免疫原 | Recombinant protein of human MORF4L1 |
| 亚型 | IgG |
| 纯化方法 | Affinity purification |
| 背景资料 | Component of the NuA4 histone acetyltransferase (HAT) complex which is involved in transcriptional activation of select genes principally by acetylation of nucleosomal histones H4 and H2A. This modification may both alter nucleosome - DNA interactions and promote interaction of the modified histones with other proteins which positively regulate transcription. This complex may be required for the activation of transcriptional programs associated with oncogene and proto-oncogene mediated growth induction； tumor suppressor mediated growth arrest and replicative senescence； apoptosis； and DNA repair. The NuA4 complex ATPase and helicase activities seem to be； at least in part； contributed by the association of RUVBL1 and RUVBL2 with EP400. NuA4 may also play a direct role in DNA repair when directly recruited to sites of DNA damage. Also component of the mSin3A complex which acts to repress transcription by deacetylation of nucleosomal histones. Required for homologous recombination repair (HRR) and resistance to mitomycin C (MMC). Involved in the localization of PALB2； BRCA2 and RAD51； but not BRCA1； to DNA-damage foci. |
| Public Immunogen Range | 1-324aa |
| 克隆类型 | Polyclonal Antibody |
| 交叉反应 | Human;Mouse;Rat |
| 应用 | WB |
| 规格 | 50ul100ul |
注意：
1.本产品仅供科研使用。请勿用于医药、临床诊断或治疗，食品及化妆品等用途。请勿存放于普通住宅区。
2.为了您的安全和健康，请穿好实验服并佩戴一次性手套和口罩操作。
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