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产品简介
英文名称 | Anti-INS Polyclonal Antibody |
靶标 | INS |
别名 | IDDM;IDDM1;IDDM2;ILPR;ins;INS_HUMAN;Insulin A chain;Insulin B chain;IRDN;MODY10;Preproinsulin;Proinsulin;Proinsulin precursor; |
宿主 | Rabbit |
预测交叉反应 | Chimpanzee;Monkey;Opossums;Camel;Goat;Horse;Sheep;Cow;Pig;Hamster;Rabbit;Cat;Dog;Duck;Turtle;Bird;Chicken;Fish;Xenopus laevis |
稀释比例 | IHC 1:50-200. |
Gene ID | 3630 |
保存 | Store at -20°C. Avoid freeze / thaw cycles. |
Swiss Prot | P01308 |
蛋白分子量 | 12/22kDa |
储存液 | Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. |
亚细胞定位 | Secreted |
免疫原 | A synthetic peptide of human INS |
亚型 | IgG |
纯化方法 | Affinity purification |
背景资料 | After removal of the precursor signal peptide, proinsulin is post-translationally cleaved into three peptides: the B chain and A chain peptides, which are covalently linked via two disulfide bonds to form insulin, and C-peptide. Binding of insulin to the insulin receptor (INSR) stimulates glucose uptake. A multitude of mutant alleles with phenotypic effects have been identified. There is a read-through gene, INS-IGF2, which overlaps with this gene at the 5' region and with the IGF2 gene at the 3' region. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2010] |
Public Immunogen Range | 15-65/110aa |
克隆类型 | Polyclonal Antibody |
交叉反应 | Human;Mouse;Rat |
应用 | IHC |
规格 | 50ul100ul |
注意:
1.本产品仅供科研使用。请勿用于医药、临床诊断或治疗,食品及化妆品等用途。请勿存放于普通住宅区。
2.为了您的安全和健康,请穿好实验服并佩戴一次性手套和口罩操作。
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