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产品简介
英文名称 | Anti-EIF4EBP1 Polyclonal Antibody |
靶标 | EIF4EBP1 |
别名 | 4E-BP1;4EBP1;4EBP1_HUMAN;BP 1;eIF4E binding protein 1;eIF4E-binding protein 1;Eif4ebp1;Eukaryotic translation initiation factor 4E-binding protein 1;PHAS-I;PHASI |
宿主 | Rabbit |
预测交叉反应 | Cow |
稀释比例 | WB 1:1000-3000;IHC 1:50-200. |
Gene ID | 1978 |
保存 | Store at -20°C. Avoid freeze / thaw cycles. |
Swiss Prot | Q13541 |
蛋白分子量 | 13kDa |
储存液 | Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. |
亚细胞定位 | Nucleus Cytoplasm |
免疫原 | A synthetic peptide of human EIF4EBP1 |
亚型 | IgG |
纯化方法 | Affinity purification |
背景资料 | This gene encodes one member of a family of translation repressor proteins. The protein directly interacts with eukaryotic translation initiation factor 4E (eIF4E), which is a limiting component of the multisubunit complex that recruits 40S ribosomal subunits to the 5' end of mRNAs. Interaction of this protein with eIF4E inhibits complex assembly and represses translation. This protein is phosphorylated in response to various signals including UV irradiation and insulin signaling, resulting in its dissociation from eIF4E and activation of mRNA translation. [provided by RefSeq, Jul 2008] |
Public Immunogen Range | 68-118/118aa |
克隆类型 | Polyclonal Antibody |
交叉反应 | Human;Mouse;Rat |
应用 | WB;IHC |
规格 | 50ul100ul |
注意:
1.本产品仅供科研使用。请勿用于医药、临床诊断或治疗,食品及化妆品等用途。请勿存放于普通住宅区。
2.为了您的安全和健康,请穿好实验服并佩戴一次性手套和口罩操作。
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