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产品简介
英文名称 | Anti-BIN1 Polyclonal Antibody |
靶标 | BIN1 |
别名 | AMPH 2;AMPH2;Amphiphysin 2;Amphiphysin II;Amphiphysin like protein;amphiphysin-like;Amphiphysin-like protein;AMPHL;Bin1;BIN1_HUMAN;Box Dependant MYC Interacting Protein 1;Box-dependent myc-interacting protein 1;Bridging integrator 1;DKFZp547F068;MGC10367;MGC105358;Myc box dependent interacting protein 1;Myc box-dependent-interacting protein 1;SH3P9 |
宿主 | Rabbit |
稀释比例 | IHC 1:50-200. |
Gene ID | 274 |
保存 | Store at -20°C. Avoid freeze / thaw cycles. |
Swiss Prot | O00499 |
蛋白分子量 | 46/47/48/50/52/53/55/56/60/65kDa |
储存液 | Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. |
亚细胞定位 | Cytoplasm |
免疫原 | A synthetic peptide of human BIN1 |
亚型 | IgG |
纯化方法 | Affinity purification |
背景资料 | This gene encodes several isoforms of a nucleocytoplasmic adaptor protein, one of which was initially identified as a MYC-interacting protein with features of a tumor suppressor. Isoforms that are expressed in the central nervous system may be involved in synaptic vesicle endocytosis and may interact with dynamin, synaptojanin, endophilin, and clathrin. Isoforms that are expressed in muscle and ubiquitously expressed isoforms localize to the cytoplasm and nucleus and activate a caspase-independent apoptotic process. Studies in mouse suggest that this gene plays an important role in cardiac muscle development. Alternate splicing of the gene results in several transcript variants encoding different isoforms. Aberrant splice variants expressed in tumor cell lines have also been described. |
Public Immunogen Range | 55-105/593aa |
克隆类型 | Polyclonal Antibody |
交叉反应 | Human |
应用 | IHC |
规格 | 50ul100ul |
注意:
1.本产品仅供科研使用。请勿用于医药、临床诊断或治疗,食品及化妆品等用途。请勿存放于普通住宅区。
2.为了您的安全和健康,请穿好实验服并佩戴一次性手套和口罩操作。
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