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产品简介
英文名称 | Anti-TGFB1 Polyclonal Antibody |
靶标 | TGFB1 |
别名 | TGFB1;CED;DPD1;LAP;TGFB;TGFbeta;TGF-β |
宿主 | Rabbit |
稀释比例 | WB 1:500-2000;IHC 1:50-200;IF 1:50-1:200. |
Gene ID | 7040 |
Swiss Prot | P01137 |
蛋白分子量 | 44kDa |
储存液 | PBS with 0.02% sodium azide,50% glycerol,pH7.3. |
亚细胞定位 | Secreted,extracellular matrix,extracellular space |
免疫原 | Recombinant fusion protein of human TGFB1. |
亚型 | IgG |
纯化方法 | Affinity purification |
背景资料 | This gene encodes a member of the transforming growth factor beta (TGFB) family of cytokines, which are multifunctional peptides that regulate proliferation, differentiation, adhesion, migration, and other functions in many cell types. Many cells have TGFB receptors, and the protein positively and negatively regulates many other growth factors. The secreted protein is cleaved into a latency-associated peptide (LAP) and a mature TGFB1 peptide, and is found in either a latent form composed of a TGFB1 homodimer, a LAP homodimer, and a latent TGFB1-binding protein, or in an active form composed of a TGFB1 homodimer. The mature peptide may also form heterodimers with other TGFB family members. This gene is frequently upregulated in tumor cells, and mutations in this gene result in Camurati-Engelmann disease. |
Public Immunogen Range | 30-278aa |
克隆类型 | Polyclonal Antibody |
规格 | 50ul100ul |
注意:
1.本产品仅供科研使用。请勿用于医药、临床诊断或治疗,食品及化妆品等用途。请勿存放于普通住宅区。
2.为了您的安全和健康,请穿好实验服并佩戴一次性手套和口罩操作。
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