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产品简介
靶标 | GPR37L1 |
别名 | Endothelin B Receptor Like Protein 2;Endothelin B receptor-like protein 2;ETBR LP 2;ETBR-LP-2;ETBR2_HUMAN;ETBRLP2;G protein coupled receptor 37 like 1;G-protein coupled receptor 37-like 1;Gpr37l1 |
宿主 | Rabbit |
稀释比例 | WB 1:1000-3000. |
Gene ID | 9283 |
保存 | Store at -20°C. Avoid freeze / thaw cycles. |
Swiss Prot | O60883 |
蛋白分子量 | 53kDa |
储存液 | Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.4. |
亚细胞定位 | Cell membrane |
免疫原 | A synthetic peptide of human GPR37L1 |
亚型 | IgG |
纯化方法 | Octanoic acid-ammonium sulfate precipitation |
背景资料 | G-protein coupled receptor. Has been shown to bind the neuroprotective and glioprotective factor prosaposin (PSAP), leading to endocytosis followed by an ERK phosphorylation cascade. However, other studies have shown that prosaposin does not increase activit. It has been suggested that GPR37L1 is a constitutively active receptor which signals through the guanine nucleotide-binding protein G(s) subunit alpha. Participates in the regulation of postnatal cerebellar development by modulating the Shh pathway. Regulates baseline blood pressure in females and protects against cardiovascular stress in males. Mediates inhibition of astrocyte glutamate transporters and reduction in neuronal N-methyl-D-aspartate receptor activity. |
Public Immunogen Range | 5-55/481aa |
克隆类型 | Polyclonal Antibody |
交叉反应 | Human |
应用 | WB |
规格 | 50ul100ul |
注意:
1.本产品仅供科研使用。请勿用于医药、临床诊断或治疗,食品及化妆品等用途。请勿存放于普通住宅区。
2.为了您的安全和健康,请穿好实验服并佩戴一次性手套和口罩操作。
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